McWhinnie has four decades of experience working in integrated resorts and hospitality across Asia, Australia and the Pacific.
McWhinnie most recently held a senior leadership position at Sands China, where he oversaw operations at eight hotels including the Venetian Macao and The Londoner Macao.
He held this position for 13 years, earning the LEED silver certification for sustainable practices in building design and construction at The Parisian Macao.
Crown Sydney’s new CEO has also worked in management for the Ishin Hotels Group in Japan and Starwood Hotels & Resorts across Asia and in Australia.
McWhinnie replaces the outgoing Simon McGrath, who will leave his post at the end of September.
Crown Resorts CEO Ciarán Carruthers said: “I’m delighted to have Mark on board to lead Crown Sydney. He is a global gaming and hospitality executive boasting an impressive track record founded on a strong culture and premium service.
“Mark’s appointment adds to the deep industry experience at Crown and is further testament to our ability to attract strong talent to our business.”
McWhinnie added: “Crown Sydney is a world-class integrated resort and Crown has a reputation across the industry for premium service delivered by a team of talented and dedicated people.
“I want to build on that status and I am also determined to play my part in realising our ambition to be a leader in the delivery of safe and responsible gaming.
“Sydney is the gateway to Australia and Crown Sydney has a significant role to play in fostering a re-emergence of activity across the hospitality and tourism sectors.”