The lottery games provider hired Galea as the company’s COO in June and the exec will now make the step up, with Mifsud moving into a consultancy role with the firm.
Galea previously worked as Chief Product Officer at Bit8 and MD at Consult Labs.
Galea said: "I’m delighted to be taking over as CEO of Helio Gaming and honoured to be given the opportunity to help build on the company’s commercial achievements to date.
"Helio Gaming’s lottery solutions are an asset for any operator looking to diversify its games portfolio."
Mifsud said: "I’m looking forward to exploring new business opportunities for Helio Gaming as we look to capitalise on promising new markets in places like Asia and Africa.
"We are making in-roads there already and freeing up my time to explore further opportunities will be beneficial."
Relax Gaming also recently named a new CEO in Tommi Maijala, with predecessor Daniel Eskola moving from the CEO role to the position of CCO.