The “get vaccinated and win” campaign allows members of the public that have been vaccinated to enter a free draw.
Between June 14 and 27, players that purchase a lottery ticket for any of the games like Loto 6/49, Joker and Loto 5/40 can enter the draw.
Players will have to write their personal information on coupons and place them in special boxes that will be located in the offices of the Romanian Lottery.
Romania could be taking inspiration from US states that have launched similar campaigns to encourage people to get vaccinated.
In the US, lotteries worth $1m have been launched to persuade the general public to receive their first dose of the Covid-19 vaccine.
The Romanian alternative will offer those who have participated in the national vaccination program the chance to win five prizes worth LEI 10,000 ($2459.91) and a prize worth LEI 50,000.
The lottery has confirmed winners will be announced on 4 July.
Romanian Lottery General Manager, Sebastian-Iacob Moga, said: "Vaccination is the only solution to hasten the end of this pandemic that has changed the lives of many Romanians and the chance to return to a normal life.
"I am confident, like many of our peers, that only if we are healthy can we enjoy life and we respond to the challenges that lie ahead."