To celebrate the agreement, Mecca Bingo has launched an exclusive Loose Women-themed bingo room on its website.
Players can match Loose Women topics and win cash prizes.
The game modes Bingo Bestie and Everyone Wins will also be available for the duration of the event.
The bingo room will be open between 8am and 12am daily, with games starting at regular intervals.
Karina Adrian, Head of Strategic Marketing at Mecca Bingo, said: “We all love to keep up with the latest trends and topics, and just like Loose Women, our customers are authentic, open and love having fun, so a partnership with ITV’s longest running panel TV show feels like a natural fit.
“As part of the partnership we’re delighted to introduce a host of new and exclusive features and with the ‘Loose Women free Winner Spinner’ everyone’s a guaranteed winner.”
Mecca Bingo has recently started a new TV advertising campaign that features players enjoying bingo in a variety of locations, including in front of the TV while watching Loose Women.
Steve Watling, Head of Games and Gaming, ITV Studios, said: "We are excited to be working with Rank on bringing the iconic Loose Women brand to Mecca Bingo players.
“The synergy, relevant lifestyle topics and chat come alive in the new games. We look forward to developing the partnership further with fun new initiatives for Mecca."
This announcement comes after Mecca Bingo pledged a full make-over of its Mecca Games online arm last year.