Both parties discussed the possibility of a cash-and-shares deal but talks ended due to a disagreement on price.
Caesars, which has 53 casinos in 14 states and overseas, had the potential to create a £6bn business, based on Friday’s share prices.
Gambling Insider understands William Hill has held plenty of discussions in the US but is remaining patient over securing the right deal, whether that is with Caesars or another company.
The operator has a five-year-plan to grow its digital platform in the US and recently struck a deal with Eldorado Resorts.
Caesars previously held talks with Eldorado over a potential merger and Gambling Insider understands William Hill is in favour of the two parties agreeing a deal.
Eldorado owns 20% of William Hill’s American business, which indicates further talks may not entirely be off the table.
Gambling Insider has reached out to Caesars for comment.